Structure of PDB 7uyb Chain A

Receptor sequence
>7uybA (length=231) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
GEYPTVNEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDEL
LLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAG
VATYASPSTRRLAEAEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHS
TDNLVVYVPSANVLYGGCAVHELSSTSAGNVADADLAEWPTSVERIQKHY
PEAEVVIPGHGLPGGLDLLQHTANVVKAHKN
3D structure
PDB7uyb Inhibitor bound VIM1
ChainA
Resolution1.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A H114 H116 H179 H84 H86 H149
BS02 ZN A D118 C198 H240 D88 C168 H210
BS03 OK0 A F62 Y67 W87 H116 D118 H179 C198 S207 N210 H240 F32 Y37 W57 H86 D88 H149 C168 S177 N180 H210
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0017001 antibiotic catabolic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7uyb, PDBe:7uyb, PDBj:7uyb
PDBsum7uyb
PubMed38387069
UniProtA0A0F7KYQ8

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