Structure of PDB 7uy8 Chain A

Receptor sequence
>7uy8A (length=156) Species: 5911 (Tetrahymena thermophila) [Search protein sequence]
SKRNQFLTSIPRVLVDCKKCDQTFLFLGADAASILKCKCGNDIYIQLKNK
IALVVKELIRNFEENAIQIDNEEFEYTHQISLVGKAKQQKMSSFTLNQKL
LSIQAMFDITKEEQENTQKVTIEKIKTIKKTLDDLLSKSQYNNLNLSNIF
TSFGLL
3D structure
PDB7uy8 Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
ChainA
Resolution4.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C1248 C1273 C1275 C17 C37 C39
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003688 DNA replication origin binding
GO:0003697 single-stranded DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006259 DNA metabolic process
GO:0006260 DNA replication
GO:0006272 leading strand elongation
GO:0006273 lagging strand elongation
GO:0071897 DNA biosynthetic process
GO:1902975 mitotic DNA replication initiation
Cellular Component
GO:0005634 nucleus
GO:0005658 alpha DNA polymerase:primase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7uy8, PDBe:7uy8, PDBj:7uy8
PDBsum7uy8
PubMed35831498
UniProtQ23AJ0

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