Structure of PDB 7uy7 Chain A

Receptor sequence
>7uy7A (length=552) Species: 5911 (Tetrahymena thermophila) [Search protein sequence]
NLKILEDVKKLYLQSFDYIKNGISSFLYKFISVNPTLLLINEKTQAKRRI
FQGEYLYGKKKIQFNIIAKNLEIERELIQFFKKPYQCYIMHNVQVFQLYY
LIDESSHVLEDDSMDFISTLTRLSDSFNSNEFVFETNYSIQISQMPKPLN
TTHFKLLQPKVVNSFEGVILQVQEGKNILQIEELIDQVYLNSRRDRFYIL
KVANGKNYMDFIEVYLVYDNEDQEAKQQLQFYLKPFQRILIFQSLKHFTK
NLKLFMISFFYSSGVQPNNSNVKNFLVSHKGVEFFSRFDIQKNELLCKDL
IKSYNKLPLSNISKLLEDEGVMIRSNMKFQVRVKKVKYFKIRLNCLNCKQ
EWTVGLKNCINCKGQQSYISYNIQVLVQDQHFLEQQAYIYLYDDLAAQFF
NITESEKKELHLHLTKNETFIQLYYSFNKDYPLSIIKFKDKIFNKDITNC
IVAYPFADIDNKIFNSQQQIIQDENLRIESEKFIQNFTENKQQIFVNGTY
ISTNYSQGQKICLKPIPCLKVMYVFPQEDIKLSALKIIEEINQLKIQIDQ
LN
3D structure
PDB7uy7 Structure of Tetrahymena telomerase-bound CST with polymerase alpha-primase.
ChainA
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A L9 K10 E13 I100 E101 L104 F108 D156 E157 L162 E163 D164 F169 L2 K3 E6 I73 E74 L77 F81 D103 E104 L109 E110 D111 F116
BS02 dna A K393 R395 N425 Y443 Y445 F473 Y477 D513 K515 K340 R342 N372 Y390 Y392 F420 Y424 D460 K462
BS03 ZN A C398 C412 C345 C359
Gene Ontology
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005694 chromosome
GO:0005697 telomerase holoenzyme complex

View graph for
Cellular Component
External links
PDB RCSB:7uy7, PDBe:7uy7, PDBj:7uy7
PDBsum7uy7
PubMed35831498
UniProtA0PGB2|TAP75_TETTS Telomerase-associated protein of 75 kDa (Gene Name=TAP75)

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