Structure of PDB 7ux8 Chain A

Receptor sequence
>7ux8A (length=378) Species: 202862 (Streptomyces drozdowiczii) [Search protein sequence]
NVSLVDESLLVGVTDEDRAVRSAHQFYERLIGLWAPAVMEAAHELGVFAA
LAEAPADSGELARRLDCDARAMRVLLDALYAYDVIDRIHDTNGFRYLLSA
EARECLLPGTLFSLVGKFMHDINVAWPAWRNLAEVVRHGARDTSGAESPN
GIAQEDYESLVGGINFWAPPIVTTLSRKLRASGRSGDATASVLDVGCGTG
LYSQLLLREFPRWTATGLDVERIATLANAQALRLGVEERFATRAGDFWRG
GWGTGYDLVLFANIFHLQTPASAVRLMRHAAACLAPDGLVAVVDQIVDAD
REPKTPQDRFALLFAASMTNTGGGDAYTFQEYEEWFTAAGLQRIETLDTP
MHRILLARRATEPSAVPEGQASENLYFQ
3D structure
PDB7ux8 Expanding the eukaryotic genetic code with a biosynthesized 21st amino acid.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A Y162 G201 C202 G203 Y207 D224 G250 D251 F252 W253 A267 N268 Y157 G196 C197 G198 Y202 D219 G245 D246 F247 W248 A262 N263
BS02 TYR A K122 L165 W172 N268 H271 F319 K117 L160 W167 N263 H266 F314
BS03 TYR A Y32 W39 Y27 W34
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008171 O-methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7ux8, PDBe:7ux8, PDBj:7ux8
PDBsum7ux8
PubMed36173166
UniProtA0A0D4WTP2

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