Structure of PDB 7uww Chain A

Receptor sequence

>7uwwA (length=632) Species: 657321 (Ruminococcus bromii L2-63)

SGSEAYFDNSKYGWKDVYVYAYGTKENAEWPGELMTKEDSGLYKASFASS
FKSEKIIFNNGLEKGNGKEQYPEAAGLSLKAGECKMLTAEKQWIDYGKPD
DHAYGYTLTANNTAFSTESLDVKLALKNADKGYYSVDGSAKKEFANGDSV
KVGEGKIGNSKVTLTLYATGADGVETEQTYTFKKTFTASKTTFSAKSDGH
TTAPESGYYGTNPEMQLGKHKTISVDGDLSDWDSSMIIAQGVANDDPRVY
MPSSMHEQPWDAYALYSAWDDDNLYFLLEMANTTYITSPEDNFAASNEAR
PWRNSIPMYLALSIDPAKQATGKAVGTNKDGSVYTNPFVWGCTNGTAKDG
GTGFTTHIDTLVAFDSNNSNGGASIFKADTQDTDGTYMFNYDTRIPIGVT
SFQAQDNKNGFKIKYANGTKSTSIFGINAPKGSRVMGDNLDMNSNWVDFF
DEGYKNSYGYVYEIAVPLNTLGIDRSYIETQGIGAMQILTYGTSGMDTLP
HDPSMLDQANLEYSYDPSTSHEKEDIDNITVPLARIGALLPDTEVNEAPF
EVNFGANLNSGQSAGTPITLLAESYHATGDVTYSFTVNGETVQNSNTDSC
VWTPSADGTYSIGVVAVDANGNKAESTKTFVV

3D structure

• PDB: 7uww The Ruminococcus amylosome protein Sas6 binds single and double helical a-glucans structures in starch
• Chain: A
• Resolution: 1.61 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GLC	A	W63 K97	W30 K64
BS02	GLC	A	Y53 W63 K101 Q103	Y20 W30 K68 Q70
BS03	GLC	A	Y53 I90 A107	Y20 I57 A74
BS04	CA	A	S527 G528 E555 D558 D560	S494 G495 E522 D525 D527
BS05	CA	A	S537 D540 E555 D558 D560	S504 D507 E522 D525 D527
BS06	CA	A	V275 D278 D294 A295 D530	V242 D245 D261 A262 D497
BS07	CA	A	S257 D259 D261 D264 E496	S224 D226 D228 D231 E463

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding

Biological Process

• GO:0030245 cellulose catabolic process

External links

• PDB: RCSB:7uww, PDBe:7uww, PDBj:7uww
• PDBsum: 7uww
• PubMed: 38177679
• UniProt: A0A2N0UYM2