Structure of PDB 7uwi Chain A

Receptor sequence
>7uwiA (length=505) Species: 9606 (Homo sapiens) [Search protein sequence]
ELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVS
AIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGS
PVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAI
TTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKV
LSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQE
GMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEA
LVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVK
LLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQD
TQVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIE
NIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAV
LFRMS
3D structure
PDB7uwi De novo mapping of alpha-helix recognition sites on protein surfaces using unbiased libraries.
ChainA
Resolution2.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A F253 Y254 T257 H260 N261 N290 K292 I296 D299 K335 R376 F107 Y108 T111 H114 N115 N144 K146 I150 D153 K189 R230
Gene Ontology
Molecular Function
GO:0045296 cadherin binding
Biological Process
GO:0007155 cell adhesion

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Molecular Function

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Biological Process
External links
PDB RCSB:7uwi, PDBe:7uwi, PDBj:7uwi
PDBsum7uwi
PubMed36534810
UniProtP35222|CTNB1_HUMAN Catenin beta-1 (Gene Name=CTNNB1)

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