Structure of PDB 7uq3 Chain A

Receptor sequence
>7uq3A (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]
STVPRLHRPSLQHFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAG
CRTVPVEVGWSQTLMTVNEFISKYIVNEPRDVGYLAQHQLFDQIPELKQD
ISIPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYI
RLYSPQESGALYPHDTHLLHNTSQVDVENPDLEKFPKFAKAPFLSCILSP
GEILFIPVKYWHYVRALDLSFSVSFWWS
3D structure
PDB7uq3 Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5.
ChainA
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.73: [protein]-arginine 3-hydroxylase.
3.4.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MN A H321 D323 H400 H133 D135 H212
BS02 O2U A Y272 W310 S318 H321 N327 L329 K336 H400 V402 S412 W414 Y84 W122 S130 H133 N139 L141 K148 H212 V214 S224 W226
External links
PDB RCSB:7uq3, PDBe:7uq3, PDBj:7uq3
PDBsum7uq3
PubMed36450832
UniProtQ8N371|KDM8_HUMAN Bifunctional peptidase and arginyl-hydroxylase JMJD5 (Gene Name=KDM8)

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