Structure of PDB 7uos Chain A

Receptor sequence
>7uosA (length=271) Species: 10116 (Rattus norvegicus) [Search protein sequence]
AVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKS
ERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLK
TYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGP
TGSVKIGDLGLATLKRASFAKAVIGTPEFMAPEMYEEKYDESVDVYAFGM
CMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCI
RQNKDERYSIKDLLNHAFFQE
3D structure
PDB7uos Structure of WNK1 inhibitor complex
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WIB A I227 G228 K233 V281 T301 F356 D368 I17 G18 K23 V71 T91 F146 D158
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7uos, PDBe:7uos, PDBj:7uos
PDBsum7uos
PubMed
UniProtQ9JIH7|WNK1_RAT Serine/threonine-protein kinase WNK1 (Gene Name=Wnk1)

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