Structure of PDB 7uoa Chain A

Receptor sequence
>7uoaA (length=203) Species: 9606 (Homo sapiens) [Search protein sequence]
ADAESLFREALSNKVDELAHFLLRKYRAKELVTKAEMLERVIKNYKRCFP
VIFGKASESLKMIFGIDVKEVDSNTYTLVTCLGLSYDGLLQIFPKTGLLI
IVLGTIAMEGDSASEEEIWEELGVMGVYDGREHTVYGEPRKLLTQDWVQE
NYLEYRQVPRYEFLWGPRALAETSYVKVLEHVVRVNARVRIAYPSLREAA
LLE
3D structure
PDB7uoa Discovery and Structural Basis of the Selectivity of Potent Cyclic Peptide Inhibitors of MAGE-A4.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A E157 S158 M161 I205 E224 E225 V228 M229 V294 N295 R297 R299 E58 S59 M62 I101 E120 E121 V124 M125 V185 N186 R188 R190
External links
PDB RCSB:7uoa, PDBe:7uoa, PDBj:7uoa
PDBsum7uoa
PubMed35522528
UniProtP43358|MAGA4_HUMAN Melanoma-associated antigen 4 (Gene Name=MAGEA4)

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