Structure of PDB 7una Chain A

Receptor sequence
>7unaA (length=142) Species: 34087 (Sphingobacterium faecium) [Search protein sequence]
LPSTALAIGYYNSFIKRVCEEIHGSECVEKIKVKSFRVDVVIPETLDDNG
VGNFTTLYNKRYGLSKATTCTNRGFPFHFKPVDIHLLDIPSTLSTIVESL
KLYLDMDYLEMRELENFAKVLKYLIGRNAATKGYVNVLTNVK
3D structure
PDB7una Cryo-EM structure of an active bacterial TIR-STING filament complex.
ChainA
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.5: NAD(+) glycohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4BW A Y161 F165 F236 P237 S262 T263 Y10 F14 F75 P76 S91 T92
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003953 NAD+ nucleosidase activity
GO:0016787 hydrolase activity
GO:0050135 NADP+ nucleosidase activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7una, PDBe:7una, PDBj:7una
PDBsum7una
PubMed35859168
UniProtA0A2T5Y4G4|CAP12_SPHFK CD-NTase-associated protein 12 (Gene Name=cap12)

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