Structure of PDB 7un8 Chain A

Receptor sequence
>7un8A (length=297) Species: 34087 (Sphingobacterium faecium) [Search protein sequence]
KKRIFIGSSSEQLTILNEIVDLLGDDVECIPWTDAFALNKSGLDSLIKQT
RLADYSILIATKDDLTKQSLTKPRDNVVFEFGLFLGAAGPEKCYLIAEED
TDLPTDLDGITVAKDKIVESIRTHLVKIAEMSQLGLLPSTALAIGYYNSF
IKRVCEEIHGSECVELEGKKIKVKSFRVDVVIPETLDDNGVGNFTTLYNK
RYGLSKATTCTNPALLGTRGFPFHFKPVDIHLLDIPSTLSTIVESLKLYL
PSNQVGQDFDMDYLEMRELENFAKVLKYLIGRNAATKGYVNVLTNVK
3D structure
PDB7un8 Cryo-EM structure of an active bacterial TIR-STING filament complex.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.5: NAD(+) glycohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C2E A Y161 S164 F165 R234 F236 P237 S262 T263 Y146 S149 F150 R219 F221 P222 S237 T238
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003953 NAD+ nucleosidase activity
GO:0016787 hydrolase activity
GO:0050135 NADP+ nucleosidase activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7un8, PDBe:7un8, PDBj:7un8
PDBsum7un8
PubMed35859168
UniProtA0A2T5Y4G4|CAP12_SPHFK CD-NTase-associated protein 12 (Gene Name=cap12)

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