Structure of PDB 7uhm Chain A

Receptor sequence
>7uhmA (length=264) Species: 522373 (Stenotrophomonas maltophilia K279a) [Search protein sequence]
APLPQLRAYTVDASWLQPMAPLQVADHTWQIGTEDLTALLVQTAEGAVLL
DGGMPQMAGHLLDNMKLRGVAPQDLRLILLSHAHADHAGPVAELKRRTGA
HVAANAETAVLLARGGSNDLHFGDGITYPPASADRIIMDGEVVTVGGIAF
TAHFMPGHTPGSTAWTWTDTRDGKPVRIAYADSLSAPGYQLKGNPRYPRL
IEDYKRSFATVRALPCDLLLTPHPGASNWNYAVGSKASAEALTCNAYADA
AEKKFDAQLARETA
3D structure
PDB7uhm Time-resolved beta-lactam cleavage by L1 metallo-beta-lactamase.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H105 H107 H181 H82 H84 H158
BS02 ZN A D109 H110 D86 H87
BS03 XQP A Y32 W38 D109 F145 H181 S206 S208 P210 H246 Y9 W15 D86 F122 H158 S183 S185 P187 H223
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008800 beta-lactamase activity
Biological Process
GO:0017001 antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7uhm, PDBe:7uhm, PDBj:7uhm
PDBsum7uhm
PubMed36450742
UniProtB2FTM1

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