Structure of PDB 7uha Chain A

Receptor sequence
>7uhaA (length=125) Species: 9606 (Homo sapiens) [Search protein sequence]
MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQ
NPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKFKRPTLRR
VRISADAMMQALLGARAKGHHHHHH
3D structure
PDB7uha Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D65 D67 S69 T71 E76 D65 D67 S69 T71 E76
BS02 WW6 A F27 L41 M45 M60 E63 V64 M80 S84 V146 I148 M153 F27 L41 M45 M60 E63 V64 M80 S84 V101 I103 M108
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005861 troponin complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:7uha, PDBe:7uha, PDBj:7uha
PDBsum7uha
PubMed35649123
UniProtP19429;
P63316|TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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