Structure of PDB 7uh3 Chain A

Receptor sequence
>7uh3A (length=415) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence]
GLYRKYIEYPVLQKILIGLILGAIVGLILGHYGYAHAVHTYVKPFGDLFV
RLLKMLVMPIVFASLVVGAASISPARLGRVGVKIVVYYLLTSAFAVTLGI
IMARLFNPGAGIHLAVGGQQFQPHQAPPLVHILLDIVPTNPFGALANGQV
LPTIFFAIILGIAITYLMNSENEKVRKSAETLLDAINGLAEAMYKIVNGV
MQYAPIGVFALIAHVMAHQGVHVVGELAKVTAAVYVGLTLQILLVYFVLL
KIYGIDPISFIKHAKDAMLTAFVTSSSSGTLPVTMRVAKEMGISEGIYSF
TLPLGATINMDGTALYQGVATFFIANALGSHLTVGQQLTIVLTAVLASIG
TAGVPGAGAIMLAMVLHSVGLPLTDPNVAAAYACILGIDAILDRGRTMVN
VTGDLTGTAIVAKTE
3D structure
PDB7uh3 Environmentally Ultrasensitive Fluorine Probe to Resolve Protein Conformational Ensembles by 19F NMR and Cryo-EM
ChainA
Resolution2.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASP A S278 T314 V355 P356 G359 R397 T398 S277 T313 V354 P355 G358 R396 T397
Gene Ontology
Molecular Function
GO:0005283 amino acid:sodium symporter activity
GO:0015108 chloride transmembrane transporter activity
GO:0015183 L-aspartate transmembrane transporter activity
GO:0015293 symporter activity
GO:0015501 glutamate:sodium symporter activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006865 amino acid transport
GO:0035725 sodium ion transmembrane transport
GO:0046942 carboxylic acid transport
GO:0070207 protein homotrimerization
GO:0070778 L-aspartate transmembrane transport
GO:0140009 L-aspartate import across plasma membrane
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:7uh3, PDBe:7uh3, PDBj:7uh3
PDBsum7uh3
PubMed
UniProtO59010|GLT_PYRHO Glutamate transporter homolog (Gene Name=PH1295)

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