Structure of PDB 7ugh Chain A

Receptor sequence
>7ughA (length=436) Species: 5763 (Naegleria fowleri) [Search protein sequence]
GAVNRVDKLVGREILDSRGNPTVEVDVYANGQKRPVATASAPSGASTGSN
EAHELRDGDKSRYLGKGVLKAVKNVNDVLGKAVEGKSLENLTELDQALID
ADGDELKSNLGGNAITACSFALATAGAAVRNEELFLYLARAFHGADKFEN
LKFRLPTPMVNILNGGKHAGGRLQIQEFMILPKENQPFREKVRCVAEVYQ
HLGKILAERAGPSAKNVGDEGGFAPNLETADEALNYIEEAIGKAGYKVGE
DVFLALDAASSEFYNSDTKKYEITQQKEFLTSEEMVEYYVQLVNRHPAII
SIEDGLEEKDYEGWKLLTERLGSKIMLVGDDLYTTNTRLIKQGIEEKWAN
ALLLKVNQIGTITEAMNAARMIFNVGQKVIVSHRSGETATTLISDLVVGI
GATHIKTGATARGERVSKYNRLLQIEEYLEQHGLLA
3D structure
PDB7ugh Crystal Structure of enolase family protein from Naegleria fowleri with bound 2-phosphoglyceric acid
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.11: phosphopyruvate hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2PG A G120 A121 E253 D406 K431 H459 R460 S461 G44 A45 E177 D330 K355 H383 R384 S385
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
GO:0016829 lyase activity
Biological Process
GO:0006096 glycolytic process
Cellular Component
GO:0000015 phosphopyruvate hydratase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ugh, PDBe:7ugh, PDBj:7ugh
PDBsum7ugh
PubMed
UniProtA0A6A5BXC3

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