Structure of PDB 7uf5 Chain A

Receptor sequence
>7uf5A (length=208) Species: 666 (Vibrio cholerae) [Search protein sequence]
NQSSLLAEFGDPITRVENALQALREGRGVLLLDDEDRENEGDIIYAVESL
TTAQMALMIRECSGIVCLCLTEAQADRLALPPMVVAFTVSIEAKHGVTTG
VSAQDRVTTIKTAANPQAKPEDLARPGHVFPLRARAGGVLARRGHTEGTV
DLMQMAGLQPAGVLCELTNPDGSMAKTPEIIEFGKLHNMPVLTIEDMVQY
RIQFDLKL
3D structure
PDB7uf5 Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.99.12: 3,4-dihydroxy-2-butanone-4-phosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 N52 A R38 E39 R151 H154 T155 L173 E175 R37 E38 R142 H145 T146 L164 E166
BS02 N4O A R38 D43 R151 G153 H154 T155 L173 E175 R37 D42 R142 G144 H145 T146 L164 E166
BS03 MN A E39 H154 E38 H145
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0008686 3,4-dihydroxy-2-butanone-4-phosphate synthase activity
GO:0016829 lyase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
Biological Process
GO:0009231 riboflavin biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7uf5, PDBe:7uf5, PDBj:7uf5
PDBsum7uf5
PubMed35802469
UniProtQ9KKP2|RIBB_VIBCH 3,4-dihydroxy-2-butanone 4-phosphate synthase (Gene Name=ribB)

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