Structure of PDB 7uf4 Chain A

Receptor sequence
>7uf4A (length=216) Species: 666 (Vibrio cholerae) [Search protein sequence]
NQSSLLAEFGDPITRVENALQALREGRGVLLLDDEDRENEGDIIYAVESL
TTAQMALMIRECSGIVCLCLTEAQADRLALPPMVVNNNSANQTAFTVSIE
AKHGVTTGVSAQDRVTTIKTAANPQAKPEDLARPGHVFPLRARAGGVLAR
RGHTEGTVDLMQMAGLQPAGVLCELTNPDGSMAKTPEIIEFGKLHNMPVL
TIEDMVQYRIQFDLKL
3D structure
PDB7uf4 Evidence for the Chemical Mechanism of RibB (3,4-Dihydroxy-2-butanone 4-phosphate Synthase) of Riboflavin Biosynthesis.
ChainA
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.1.99.12: 3,4-dihydroxy-2-butanone-4-phosphate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 N46 A R38 T94 R151 G153 H154 T155 E175 R37 T93 R150 G152 H153 T154 E174
BS02 5RP A R38 E39 D43 C68 F96 R151 G153 H154 T155 E175 R37 E38 D42 C67 F95 R150 G152 H153 T154 E174
BS03 MN A E39 H154 E38 H153
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0008686 3,4-dihydroxy-2-butanone-4-phosphate synthase activity
GO:0016829 lyase activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
Biological Process
GO:0009231 riboflavin biosynthetic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7uf4, PDBe:7uf4, PDBj:7uf4
PDBsum7uf4
PubMed35802469
UniProtQ9KKP2|RIBB_VIBCH 3,4-dihydroxy-2-butanone 4-phosphate synthase (Gene Name=ribB)

[Back to BioLiP]