Structure of PDB 7uah Chain A

Receptor sequence
>7uahA (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
DCGKPQVEPKKCPVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWV
LTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIA
LLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLK
EAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDAGGPLVCF
EKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
3D structure
PDB7uah Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors.
ChainA
Resolution1.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M63 A H603 D646 R719 D735 S736 C737 Q738 T759 S760 W761 G762 G764 H55 D98 R171 D187 S188 C189 Q190 T211 S212 W213 G214 G216
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7uah, PDBe:7uah, PDBj:7uah
PDBsum7uah
PubMed36710259
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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