Structure of PDB 7u6m Chain A

Receptor sequence
>7u6mA (length=327) Species: 556 (Dickeya chrysanthemi) [Search protein sequence]
DDKLPNIVILATGGTIAGSAATGTQTTGYKIGALGVDTLINAVPEVKKLA
NVKGEQFSNMASQNMTGDVVLKLSQRVNELLARDDVDGVVITHGTDTVEE
SAYFLHLTVKSDKPVVFVAAMRPATAISADGPMNLLEAVRVAGDKQSRGR
GVMVVLNDRIGSARYITKTNASTLDTFKANEEGYLGVIIGNRIYYQNRID
KLHTTRSVFDVRGLTSLPKVDILYGYQDDPEYLYDAAIQHGVKGIVYAGM
GAGQVSVRGIAGMRKAMEKGVVVIRSTRTGNGIVPPDEELPGLVSDSLNP
AHARILLMLALTRTSDPKVIQEYFHTY
3D structure
PDB7u6m In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia.
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.1: asparaginase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASP A T15 A61 S62 Q63 G94 T95 D96 T15 A61 S62 Q63 G94 T95 D96
Gene Ontology
Molecular Function
GO:0004067 asparaginase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006528 asparagine metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7u6m, PDBe:7u6m, PDBj:7u6m
PDBsum7u6m
PubMed35979719
UniProtP06608|ASPG_DICCH L-asparaginase (Gene Name=ansB)

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