Structure of PDB 7u3i Chain A

Receptor sequence
>7u3iA (length=153) Species: 9606 (Homo sapiens) [Search protein sequence]
SGSKFRGHQKSKGNSYDVEVVLQHVDTGNSYLCGYLKIKTEEYPTLTTFF
EGEIISKKHPFLTRKWDADEDVDRKHWGKFLAFYQYADFDYEELKNGDYV
FMRWKEQFLVPDHTGASFAGFYYICFQKSAASIEGYYYHRSSEWYQSLNL
THV
3D structure
PDB7u3i Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
ChainA
Resolution1.991 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 L5X A Q132 I161 L171 T173 E237 S253 Y258 Y273 Q9 I38 L46 T48 E106 S117 Y122 Y137
External links
PDB RCSB:7u3i, PDBe:7u3i, PDBj:7u3i
PDBsum7u3i
PubMed36117290
UniProtQ8IVV7|GID4_HUMAN Glucose-induced degradation protein 4 homolog (Gene Name=GID4)

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