Structure of PDB 7u0g Chain A

Receptor sequence
>7u0gA (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
3D structure
PDB7u0g Structural mechanism of LIN28B nucleosome targeting by OCT4.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y41 R42 T45 R72 R83 F84 R116 V117 T118 M120 Y4 R5 T8 R35 R46 F47 R79 V80 T81 M83
BS02 dna A R40 Y41 P43 G44 V46 R63 K64 L65 P66 R69 R3 Y4 P6 G7 V9 R26 K27 L28 P29 R32
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0045296 cadherin binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010467 gene expression
GO:0032200 telomere organization
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7u0g, PDBe:7u0g, PDBj:7u0g
PDBsum7u0g
PubMed37327775
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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