Structure of PDB 7tzp Chain A

Receptor sequence
>7tzpA (length=245) Species: 484021 (Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044) [Search protein sequence]
AMKLASKTAIVTGAARGIGFGIAQVLAREGARVIIADRDAHGEAAAASLR
ESGAQALFISCNIAEKTQVEALFSQAEEAFGPVDILVNNAGINRDAMLHK
LTEADWDTVIDVNLKGTFLCMQQAAIRMRERGAGRIINIASASWLGNVGQ
TNYSASKAGVVGMTKTACRELAKKGVTVNAICPGFIDTDMTRGVPENVWQ
IMVSKIPAGYAGEAKDVGECVAFLASDGARYINGEVINVGGGMVL
3D structure
PDB7tzp A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.100: 3-oxoacyl-[acyl-carrier-protein] reductase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAI A G12 R15 G16 I17 D36 R37 C60 N88 G90 I91 V111 S140 Y152 K156 P182 I185 T187 T190 G13 R16 G17 I18 D37 R38 C61 N89 G91 I92 V112 S141 Y153 K157 P183 I186 T188 T191
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:7tzp, PDBe:7tzp, PDBj:7tzp
PDBsum7tzp
PubMed36695589
UniProtA0A332H2K8

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