Structure of PDB 7tza Chain A

Receptor sequence
>7tzaA (length=296) Species: 208963 (Pseudomonas aeruginosa UCBPP-PA14) [Search protein sequence]
SHMLRLSAPGQLDDDLCLLGDVQVPVFLLRLGEASWALVEGGISRDAELV
WADLCRWVADPSQVHYWLITHKHYDHCGLLPYLCPRLPNVQVLASERTCQ
AWKSESAVRVVERLNRQLLRQRLPEACAWDALPVRAVADGEWLELGPRHR
LQVIEAHGHSDDHVVFYDVRRRRLFCGDALGEFDEAEGVWRPLVFDDMEA
YLESLERLQRLPTLLQLIPGHGGLLRGRLAADGAESAYTECLRLCRRLLW
RQSMGESLDELSEELHRAWGGQSVDFLPGELHLGSMRRMLEILSRQ
3D structure
PDB7tza The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H69 H71 H74 H159 D178 H71 H73 H76 H159 D178
BS02 FE A D73 H74 D178 H221 D75 H76 D178 H221
BS03 KYX A H71 Y72 D73 A105 V108 L112 E182 L193 F195 H221 L277 L281 H282 S285 H73 Y74 D75 A107 V110 L114 E182 L193 F195 H221 L277 L281 H282 S285
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7tza, PDBe:7tza, PDBj:7tza
PDBsum7tza
PubMed35985643
UniProtA0A0H2Z6F6

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