Structure of PDB 7tv0 Chain A

Receptor sequence
>7tv0A (length=134) Species: 9606 (Homo sapiens) [Search protein sequence]
NPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLN
LPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPG
DDIVLMAEALEKLFLQKINELPTEETEIMIVQAK
3D structure
PDB7tv0 Binding of the SARS-CoV-2 envelope E protein to human BRD4 is essential for infection.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q78 F79 W81 Q35 F36 W38
BS02 peptide A W81 F83 V87 K91 L92 I146 W38 F40 V44 K48 L49 I103
External links
PDB RCSB:7tv0, PDBe:7tv0, PDBj:7tv0
PDBsum7tv0
PubMed35716662
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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