Structure of PDB 7trl Chain A

Receptor sequence
>7trlA (length=90) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEFISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKC
FCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVD
3D structure
PDB7trl Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2.
ChainA
Resolution1.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G312 L313 R314 C315 W316 W329 G56 L57 R58 C59 W60 W73
BS02 ZN A C306 C309 H326 C333 C50 C53 H70 C77
External links
PDB RCSB:7trl, PDBe:7trl, PDBj:7trl
PDBsum7trl
PubMed37524969
UniProtQ13490|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (Gene Name=BIRC2)

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