Structure of PDB 7toa Chain A

Receptor sequence
>7toaA (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
PGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPM
DMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEK
IFLQKVAQMPQEEVEL
3D structure
PDB7toa BRD3-BD1 in complex with RaPID linear peptide 3xAcK.1 (triAcK.1)
ChainA
Resolution1.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W57 P58 K67 L68 N69 L70 N116 T119 D120 D121 I122 M125 W26 P27 K36 L37 N38 L39 N85 T88 D89 D90 I91 M94
External links
PDB RCSB:7toa, PDBe:7toa, PDBj:7toa
PDBsum7toa
PubMed37992806
UniProtQ15059|BRD3_HUMAN Bromodomain-containing protein 3 (Gene Name=BRD3)

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