Structure of PDB 7tlr Chain A

Receptor sequence
>7tlrA (length=408) Species: 1382 (Lancefieldella parvula) [Search protein sequence]
GMTDTEVAQITDNPYKADFPILAANPKVAYLDSAYTSQRPRVVIEAQSRF
YETMNASVDATAAIEDARASIAKFIGAVDKNDKPESQQIIFTRNTSEALN
LVASSLGRYALKPGDDVVISIMEHHSNIIPWQQICKATGANLVYLRMNSQ
YQITPEEIASKITERAKIVSVTHVSNVLGTRNDIKAIAKRTHAMGAYMVV
DAAQSAPHILVNVHDLDCDLLAFSAHKMCGPMGIGVLWGRAELLNAMPPF
LTGGEMIDSVTETGAVWAPVPEKFEAGTQDAAGIYATGAAIKYLNGLDMA
KIEKREELLARYLVQQLCTLDFVDIVGSKLGQNHVGAVAFNVRGVHPHDV
SSILDMNNVCIRAGHHCAEPLLIELHESSTCRASVAFYNDKHDIDQLIEG
LNQVWKIF
3D structure
PDB7tlr Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.1.7: cysteine desulfurase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A N102 T103 S104 H132 D209 A211 Q212 S232 H234 K235 N94 T95 S96 H124 D201 A203 Q204 S224 H226 K227
BS02 PLP A G285 T286 G277 T278
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
GO:0031071 cysteine desulfurase activity
Biological Process
GO:0006534 cysteine metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7tlr, PDBe:7tlr, PDBj:7tlr
PDBsum7tlr
PubMed35122247
UniProtC8W9P2

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