Structure of PDB 7ti7 Chain A

Receptor sequence
>7ti7A (length=442) Species: 470 (Acinetobacter baumannii) [Search protein sequence]
GLKVVAGLGISGVSAVNFLHEQGYQVAVTDSRPTPPGHDQIPAGVKTSFG
QLDQELLLQAEEIILSPGLAPQLPEIQAAIAKGISVVGDIQLLRRATDVP
IVAITGSNAKSTVTTLIGLMAKDAGKKVAVGGNLGRPALDLLKDQPELLV
LELSSFQLETTSHLNAEVAVVLNMSEDHLDRHGNMLGYHQAKHRIFQGAK
KVVFNRDDALSRPLVPDTTPMQSFGLNAPDLNQYGVLRDADGTLWLARGL
QRLIKSSDLYIQGMHNVANALACLALGEAIGLPMESMLETLKQFKGLEHR
CEYVKTVHDVRYYNDSKGTNVGATLAAIDGLGAAIEVKKGKVALILGGQG
KGQDFGPLRSSIEKYAKVVVLIGEDAPVIEQAIQGATKILHAATLKEAVE
LCQRETQAEDVVLLSPACASFDMFKSYNDRGQQFVACVNSLV
3D structure
PDB7ti7 Crystal Structure of UDP-N-acetylmuramoylalanine-D-glutamate ligase from Acinetobacter baumannii AB5075-UW in complex with ADP
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.9: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N114 A115 K116 S117 T118 H271 N275 R306 D321 K323 G324 A329 A332 N108 A109 K110 S111 T112 H265 N269 R300 D315 K317 G318 A323 A326
BS02 CA A S117 E158 S111 E152
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008764 UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009058 biosynthetic process
GO:0009252 peptidoglycan biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ti7, PDBe:7ti7, PDBj:7ti7
PDBsum7ti7
PubMed
UniProtB7H1N2|MURD_ACIB3 UDP-N-acetylmuramoylalanine--D-glutamate ligase (Gene Name=murD)

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