Structure of PDB 7ths Chain A

Receptor sequence
>7thsA (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
DCGKPQVEPKKCPVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWV
LTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIA
LLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGAGLLK
EAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDAGGPLVCF
EKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
3D structure
PDB7ths Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 I5Y A H603 D646 R719 D735 S736 C737 Q738 T759 S760 W761 G762 G764 C765 H55 D98 R171 D187 S188 C189 Q190 T211 S212 W213 G214 G216 C217
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7ths, PDBe:7ths, PDBj:7ths
PDBsum7ths
PubMed36710259
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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