Structure of PDB 7th7 Chain A

Receptor sequence
>7th7A (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
NPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGST
FHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMAN
AGPNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGSKSGRT
SKKIVITDCGQLS
3D structure
PDB7th7 Discovery and molecular basis of subtype-selective cyclophilin inhibitors.
ChainA
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 I5E A R97 F102 Q105 G114 T115 G116 K118 S119 S123 R124 A143 N144 A145 G151 Q153 F155 W163 H168 R53 F58 Q61 G70 T71 G72 K74 S75 S79 R80 A99 N100 A101 G107 Q109 F111 W119 H124
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7th7, PDBe:7th7, PDBj:7th7
PDBsum7th7
PubMed36163383
UniProtP30405|PPIF_HUMAN Peptidyl-prolyl cis-trans isomerase F, mitochondrial (Gene Name=PPIF)

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