Structure of PDB 7tgq Chain A

Receptor sequence
>7tgqA (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
SEEICLDHLCKGCPLNGSCSKVHFHLPYRWQMLIGKTWTDFEHMETIEKG
YCNPGIHLCSVGSYTINFRVMSCDSFPIRRLSTPSSVTKPANSVFTTKWI
WYWKNESGTWIQYGENSNVDSSYLESLYQSCPRGVVPFQAGSRNYELSFQ
GMIQTNIASKTQKDVIRRPTFVPQWYVQQMKR
3D structure
PDB7tgq Poly(ADP-ribose) potentiates ZAP antiviral activity.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C513 C521 C527 H531 C5 C13 C19 H23
BS02 APR A W611 S631 A654 R657 Y659 Q668 N670 S673 T675 K677 W103 S117 A140 R143 Y145 Q154 N156 S159 T161 K163
External links
PDB RCSB:7tgq, PDBe:7tgq, PDBj:7tgq
PDBsum7tgq
PubMed35130321
UniProtQ7Z2W4|ZCCHV_HUMAN Zinc finger CCCH-type antiviral protein 1 (Gene Name=ZC3HAV1)

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