Structure of PDB 7tgk Chain A

Receptor sequence

>7tgkA (length=592) Species: 35619 (Streptomyces griseoflavus)

HMSLTDAVAHLSPERWEEANRLLVRKALAEFAHERLFTPEPADGQDGRYV
VRSDDGLTSYRFTAVRRALDHWQVDAGSITRTRDGAELPLAALDFFIELR
HTLGLSDEILPVYLEEISSTLSGTCYKLTKPQVTAAGLLEGGFQALESGM
TEGHPCFVANNGRLGFGVDEYLAYAPETAHPVRLVWLAAHRSRAAFTAGA
GIDYASFVRQELGEETVERFDGVLRGRGLDPADYLLIPVHPWQWWNKLSV
TFAAEVARQNLVCLGESDDEYLAQQSIRTFFNATHPEKHYVKTALSVLNM
GFMRGLSAAYMEATPAINDWLDRLIDNDPVLKSTGLSIIRERAAVGYRHL
EYEAATDRYSPYRKMLAALWRESPVPALRDGESLTTMAALVHVDHEGRSV
AGELIARSGLAPTAWLRHYLRAYYTPLLHSFYAYDLAFMPHGENTILVLK
DGVVQRAVYKDIAEEIVVMDPDAVLPPEVRRVRAEVPEDMKLLSIFTDVF
DCFFRFLAAGLATEEVLAEDDFWRTVAEVTREYQEAHPELDDRFRQYDLF
APEFALSCLNRLQLRDNRQMVDLADPSAALQLVGTLRNPLAG

3D structure

• PDB: 7tgk An acyl-adenylate mimic reveals the structural basis for substrate recognition by the iterative siderophore synthetase DesD.
• Chain: A
• Resolution: 2.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ATP	A	G152 H153 Q274 S275 R277 T278 K291 N298 M299 R303 R370 H440 E442 N443 D460	G153 H154 Q275 S276 R278 T279 K292 N299 M300 R304 R371 H441 E443 N444 D461
BS02	MG	A	D460 E463 E464	D461 E464 E465
BS03	MG	A	E442 N443 D460	E443 N444 D461

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sat Nov 16 16:42:12 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '7tgk', asym_id = 'A', title = 'An acyl-adenylate mimic reveals the structural b...ion by the iterative siderophore synthetase DesD.'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='7tgk', asym_id='A', title='An acyl-adenylate mimic reveals the structural b...ion by the iterative siderophore synthetase DesD.')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0019290', uniprot = '', pdbid = '7tgk', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0019290', uniprot='', pdbid='7tgk', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>