Structure of PDB 7tfk Chain A

Receptor sequence
>7tfkA (length=360) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
REEDKLWTVKYAPTNLQQVCGNKGSVMKLKNWLANWENSKKNSFKHAGKD
GSGVFRAAMLYGPPGIGKTTAAHLVAQELGYDILEQNANGKHFVIIMDEV
DGMGVGQLAQFCRKTSTPLILICNERNLPKMRPFDRVCLDIQFRRPDANS
IKSRLMTIAIREKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTIN
HENINEISKAWEKNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYF
DDFDFTPLMIQENYLSTRPSVLKPGQSHLEAVAEAANCISLGDIVEKKIR
SSEQLWSLLPLHAVLSSVYPASKVAGHMAGRINFTAWLGQNSKSAKYYRL
LQEIHYHTRL
3D structure
PDB7tfk Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
ChainA
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000278 mitotic cell cycle
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tfk, PDBe:7tfk, PDBj:7tfk
PDBsum7tfk
PubMed35829698
UniProtP38630|RFC1_YEAST Replication factor C subunit 1 (Gene Name=RFC1)

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