Structure of PDB 7t92 Chain A

Receptor sequence
>7t92A (length=298) Species: 573729 (Thermothelomyces thermophilus ATCC 42464) [Search protein sequence]
TRPAFRVGQVDAELLDEELVELLRGQVREALRYVGGGGSGVAQDWEAEIS
LALRAVLFKLTVWDHDATYGAALQNLKYTDARRDGPALAPPSRWQKALYG
LVTVGGRYLWAKWEDWLLEQDDPSPRVKRLARWTSSLSTLHASAALVSFL
VFLLHGRYRTLLDRLLRMRLAPPTSQVSFEYLNRQLVWHAFTEFLLFVLP
LVGINRWRRWLARTWRDKKGEYSFLPERTCAICYRDQNSVVGSAQTDITN
PYEAIPCGCTYCFVCLATRIEREEGEGWPCLRCGELIKECKPWNGDVL
3D structure
PDB7t92 A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.36: RING-type E3 ubiquitin transferase (cysteine targeting).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C311 C334 C257 C280
BS02 ZN A C270 C316 C319 C230 C262 C265
BS03 CLR A W127 H162 W110 H141
BS04 LBN A R209 W213 F216 L220 R184 W188 F191 L195
BS05 LBN A W240 R241 W215 R216
BS06 LBN A K76 W80 K59 W63
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
Biological Process
GO:0007031 peroxisome organization
GO:0016558 protein import into peroxisome matrix
Cellular Component
GO:0005778 peroxisomal membrane

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Cellular Component
External links
PDB RCSB:7t92, PDBe:7t92, PDBj:7t92
PDBsum7t92
PubMed35768507
UniProtG2Q1C9|PEX2_THET4 Peroxisome assembly protein 2 (Gene Name=PEX2)

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