Structure of PDB 7t8d Chain A

Receptor sequence
>7t8dA (length=259) Species: 9606 (Homo sapiens) [Search protein sequence]
GCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGT
DVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRT
VIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYS
TDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYT
SADATINFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLN
MVTYDIKLS
3D structure
PDB7t8d Quantitative differentiation of benign and misfolded glaucoma-causing myocilin variants on the basis of protein thermal stability.
ChainA
Resolution1.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D380 N428 A429 I477 D478 D137 N185 A186 I234 D235
External links
PDB RCSB:7t8d, PDBe:7t8d, PDBj:7t8d
PDBsum7t8d
PubMed36579626
UniProtQ99972|MYOC_HUMAN Myocilin (Gene Name=MYOC)

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