Structure of PDB 7t7t Chain A

Receptor sequence

>7t7tA (length=466) Species: 55188 (Citrus unshiu)

MGRDEMQMSEAKRAYRSAKEEGNRQEEARWANVIGDILKNRGEYVEALKW
FRIDYDVSVKYLPEKHLLPTCQSLGEVYLRLEHFKDALIYQKKHLELAKD
ASDLVEQQRACTQLGRTYYEMFLRYSIRNAKKYFKSAMKLAQTLKSSFLK
EYIDAHNNIGMLQMEDNLEEAKKLLIRGLEICNEEDDDGRSRLHHNLGNV
YMELRMWDKSREHIEQDIIICKKIEHRQGEAKGYINLGELHYRVQKYDEA
ILCYQKALNLAQSMEDEDALASQIDQNIETVKKAIEVMDELKKEEQNLKK
LTRNMIIAKGTSQERKSLLQQNASLDCLIEKSSMIFAWLKHCEYAKRKKR
IASELCDKGKLSDSFLVIGESYQKLRKFNKAIKWYTKSWEMYKSIGNLEG
QALAKVNMGNVLDSNGDWAGALDAFQEGYRIAVEANLPSVQLSALENMHY
SHMIRFDNIEEARRLQ

3D structure

• PDB: 7t7t The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication.
• Chain: A
• Resolution: 3.17 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	E26 R29 W30 N32 V33 D54 H66 P69 T70 Q72 S73 R109 Q113 R116 Y119 E163 N170 M173 R209 H212 N216 D234 K249 N253 E256 Y259 Q293 N294 T297 S350 M351 F353 N424 N427 D430 E463 N464	E26 R29 W30 N32 V33 D54 H66 P69 T70 Q72 S73 R109 Q113 R116 Y119 E151 N158 M161 R192 H195 N199 D217 K232 N236 E239 Y242 Q276 N277 T280 S333 M334 F336 N407 N410 D413 E446 N447

Gene Ontology

Biological Process

• GO:0006325 chromatin organization
• GO:0009933 meristem structural organization
• GO:0040029 epigenetic regulation of gene expression
• GO:0072423 response to DNA damage checkpoint signaling

Cellular Component

• GO:0005634 nucleus

External links

• PDB: RCSB:7t7t, PDBe:7t7t, PDBj:7t7t
• PDBsum: 7t7t
• PubMed: 35298257
• UniProt: A0A2H5Q1B8|TONSL_CITUN Protein TONSOKU (Gene Name=TSK)