Structure of PDB 7t6i Chain A

Receptor sequence
>7t6iA (length=183) Species: 9606 (Homo sapiens) [Search protein sequence]
IKADHVSTYAAFVQTHRPTGEFMFEFDEDEQFYVDLDKKETVWHLEEFGR
AFSFEAQGGLANIAILNNNLNTLIQRSNHTQAANDPPEVTVFPKEPVELG
QPNTLICHIDRFFPPVLNVTWLCNGEPVTEGVAESLFLPRTDYSFHKFHY
LTFVPSAEDVYDCRVEHWGLDQPLLKHWEATSG
3D structure
PDB7t6i Human T cells recognize HLA-DP-bound peptides in two orientations.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y9 Q31 R50 A51 F52 S53 F54 N62 I65 N68 N69 T72 R76 Y9 Q31 R50 A51 F52 S53 F54 N62 I65 N68 N69 T72 R76
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7t6i, PDBe:7t6i, PDBj:7t6i
PDBsum7t6i
PubMed36442096
UniProtQ95HB9

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