Structure of PDB 7t2d Chain A

Receptor sequence
>7t2dA (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
IKADHVSTYAAFVQTHRPTGEFMFEFDEDEMFYVDLDKKETVWHLEEFGQ
AFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVELG
QPNTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHY
LTFVPSAEDFYDCRVEHWGLDQPLLKHWEA
3D structure
PDB7t2d CD4 + T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y9 A11 F52 S53 G58 A61 N62 I65 N68 N69 T72 Y9 A11 F52 S53 G58 A61 N62 I65 N68 N69 T72
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7t2d, PDBe:7t2d, PDBj:7t2d
PDBsum7t2d
PubMed37100059
UniProtP20036|DPA1_HUMAN HLA class II histocompatibility antigen, DP alpha 1 chain (Gene Name=HLA-DPA1)

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