Structure of PDB 7t1u Chain A

Receptor sequence
>7t1uA (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
APWQAEEWYFGKITRRESERLLLNAENPRGTFLVREGQSQPDYVLSVSDF
DNAKGLNVKHYIIRKLDSGFYITSRTQFNSLQQLVAYYSKHADGLCHRLT
TVCPT
3D structure
PDB7t1u Engineered SH2 Domains for Targeted Phosphoproteomics.
ChainA
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R158 R178 S182 Q183 K202 H203 Y204 I205 I216 T217 G238 R15 R35 S39 Q40 K59 H60 Y61 I62 I72 T73 G94
BS02 ZN A D192 D194 C240 D49 D51 C96
External links
PDB RCSB:7t1u, PDBe:7t1u, PDBj:7t1u
PDBsum7t1u
PubMed35613471
UniProtP12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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