Structure of PDB 7t1l Chain A

Receptor sequence
>7t1lA (length=99) Species: 9606 (Homo sapiens) [Search protein sequence]
KPLHEQLWYHGAIPRAEVAELLVHSGDFLVRESETVKGAYALSVLWDGLP
RHFLIQSLDNLYRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVP
3D structure
PDB7t1l Engineered SH2 Domains for Targeted Phosphoproteomics.
ChainA
Resolution1.35 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R16 R32 S34 E35 T36 R52 H53 F54 Q57 R15 R31 S33 E34 T35 R51 H52 F53 Q56
BS02 peptide A E35 T36 V37 K38 A40 E34 T35 V36 K37 A39
External links
PDB RCSB:7t1l, PDBe:7t1l, PDBj:7t1l
PDBsum7t1l
PubMed35613471
UniProtP07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps (Gene Name=FES)

[Back to BioLiP]