Structure of PDB 7t1k Chain A

Receptor sequence
>7t1kA (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
GKPLHEQLWYHGAIPRAEVAELLVHSGDFLVREGQSQPDYVLSVLWDGLP
RHFIIQSLDNLYRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVPK
SR
3D structure
PDB7t1k Engineered SH2 Domains for Targeted Phosphoproteomics.
ChainA
Resolution1.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R16 R32 G34 Q35 S36 Q37 R51 H52 F53 I54 Q56 L64 R16 R32 G34 Q35 S36 Q37 R51 H52 F53 I54 Q56 L64
External links
PDB RCSB:7t1k, PDBe:7t1k, PDBj:7t1k
PDBsum7t1k
PubMed35613471
UniProtP07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps (Gene Name=FES)

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