Structure of PDB 7su4 Chain A

Receptor sequence
>7su4A (length=117) Species: 632 (Yersinia pestis) [Search protein sequence]
AMDIVFIEELSVITTIGVYDWEQTIQQKLVFDIEMGWDNRKAAGSDDVND
CLSFADISEAVIQHVGSQRFALVERVAEEVAELLLRRFNSPWVRIKVSKP
GAVAQAKNVGVIIERGQ
3D structure
PDB7su4 Dihydroneopterin aldolase (DHNA) Tyr53Phe from Yersinia pestis co-crystallized with 7,8-dihydroneopterin
ChainA
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.2.25: dihydroneopterin aldolase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NPR A V17 Y18 E21 L71 V72 E73 K98 A101 V18 Y19 E22 L72 V73 E74 K99 A102
BS02 NPR A C50 L51 S52 F53 C51 L52 S53 F54
Gene Ontology
Molecular Function
GO:0004150 dihydroneopterin aldolase activity
GO:0016301 kinase activity
GO:0016829 lyase activity
Biological Process
GO:0006760 folic acid-containing compound metabolic process
GO:0016310 phosphorylation
GO:0046654 tetrahydrofolate biosynthetic process
GO:0046656 folic acid biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7su4, PDBe:7su4, PDBj:7su4
PDBsum7su4
PubMed
UniProtQ8CZR7

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