Structure of PDB 7ssg Chain A

Receptor sequence
>7ssgA (length=382) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
RAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
LVCGDVGFGKTEVAMRAAFLAVDNHKQVAVLVPTTLLAQQHYDNFRDRFA
NWPVRIEMISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKFKDLG
LLIVDEEHRFGVRHKERIKAMRANVDILTLTATPIPRTLNMAMSGMRDLS
IIATPPARRLAVKTFVREYDSMVVREAILREILRGGQVYYLYNDVENIQK
AAERLAELVPEARIAIGHGQMRERELERVMNDFHHQRFNVLVCTTIIETG
IDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWLLTPHPKAMTT
DAQKRLEAIASLEDLGAGFALATHDLEIRGAG
3D structure
PDB7ssg Mechanism of transcription modulation by the transcription-repair coupling factor.
ChainA
Resolution5.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R929 D949 L950 R355 D375 L376
BS02 dna A S688 A689 G735 V736 R737 R929 S114 A115 G161 V162 R163 R355
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0015616 DNA translocase activity
GO:0016787 hydrolase activity
GO:0043175 RNA polymerase core enzyme binding
Biological Process
GO:0000716 transcription-coupled nucleotide-excision repair, DNA damage recognition
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006355 regulation of DNA-templated transcription
GO:0006974 DNA damage response
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:1990391 DNA repair complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ssg, PDBe:7ssg, PDBj:7ssg
PDBsum7ssg
PubMed35641110
UniProtP30958|MFD_ECOLI Transcription-repair-coupling factor (Gene Name=mfd)

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