Structure of PDB 7ssb Chain A

Receptor sequence
>7ssbA (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
STGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQG
ARGDTFFIISKGTVNVTREDSDPVFLRTLGKGDWFGEKALQGEDVRTANV
IAAEAVTCLVIDRDSFKHLIGGL
3D structure
PDB7ssb Optimization and Mechanistic Investigations of Novel Allosteric Activators of PKG1 alpha.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.12: cGMP-dependent protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 B4I A T236 F273 W304 F336 T19 F56 W84 F116
Gene Ontology
Molecular Function
GO:0004692 cGMP-dependent protein kinase activity
GO:0005524 ATP binding
GO:0008603 cAMP-dependent protein kinase regulator activity
Biological Process
GO:0001932 regulation of protein phosphorylation
Cellular Component
GO:0005952 cAMP-dependent protein kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ssb, PDBe:7ssb, PDBj:7ssb
PDBsum7ssb
PubMed35878399
UniProtQ13976|KGP1_HUMAN cGMP-dependent protein kinase 1 (Gene Name=PRKG1)

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