Structure of PDB 7spy Chain A

Receptor sequence
>7spyA (length=322) Species: 184922 (Giardia lamblia ATCC 50803) [Search protein sequence]
ATYMLPSLHDILDQHTYKWIFFGGKGGVGKTTTSSSFSVLMAETRPNEKF
LLLSTNPAHNISDAFDQKFGKAPTQVSGIPNLYAMEVDASGDMFGGLNDL
ITCASSFIKDGTFPGMDEMWSFINLIKLIDTNEYSTVIFDTAPTGHTLRF
LELPETVNKVLEIFTRLKDNMGGMLSMVMQTMGLSQNDIFGLIDKTYPKI
DVVKRISAEFRDPSLCTFVGVCIPEFLSLYETERLVQRLAVLDMDCHAIV
INFVLDANAATPCSMCRSRARMQNKYIDQINELYDDFNIVLSPLRHDEVR
GIANLRDYAETLIKPYRFCWSA
3D structure
PDB7spy Structurally derived universal mechanism for the catalytic cycle of the tail-anchored targeting factor Get3.
ChainA
Resolution2.23 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A G23 G24 G26 K27 T28 T29 N276 F277 R319 V323 G26 G27 G29 K30 T31 T32 N252 F253 R295 V299
BS02 ZN A C287 C290 C263 C266
BS03 ZN A H6 D10 H9 D13
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0045048 protein insertion into ER membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7spy, PDBe:7spy, PDBj:7spy
PDBsum7spy
PubMed35851188
UniProtA8B3G9|ASNA_GIAIC ATPase ASNA1 homolog (Gene Name=GL50803_7953)

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