Structure of PDB 7sn6 Chain A

Receptor sequence
>7sn6A (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
LGSTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRPV
DGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHR
RDFW
3D structure
PDB7sn6 A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A M383 E397 D401 E405 L449 G451 R452 K453 F454 M12 E26 D30 E34 L78 G80 R81 K82 F83
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7sn6, PDBe:7sn6, PDBj:7sn6
PDBsum7sn6
PubMed35780835
UniProtP26368|U2AF2_HUMAN Splicing factor U2AF 65 kDa subunit (Gene Name=U2AF2)

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