Structure of PDB 7smz Chain A

Receptor sequence
>7smzA (length=395) Species: 1348799 (Mycobacterium marinum ATCC BAA-535) [Search protein sequence]
IKPDVDLTDGNFYASRQAREAYRWMRANQPVFRDRNGLAAASTYQAVIDA
ERQPELFSNAGGIRPDQDALPMMIDMDDPAHLLRRKLVNAGFTRKRVKDK
ERSIAQLCDTLIDAVCERGECDFVRDLAAPLPMAVIGDMLGVLPEQREMF
LRWSDDLVTFLSSHVSQEDFQVTIDAFAAYNDFTRATIAARRAEPTDDLV
SVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLSGGSEQLLRNRDQ
WDLLQSDRELLPGAIEEMLRWTAPVKNMCRMLTADTEFHGTALSEGEKIM
LLFESANFDEAVFTDPEKFDIQRNPNSHLAFGFGTHFCMGNQLARLELSL
MTARVVQRLPDLRLADQDSRLPLRPANFVSGLESMPVVFTPSRPL
3D structure
PDB7smz The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum.
ChainA
Resolution2.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K2B A M77 F182 L229 I232 F383 M72 F177 L224 I227 F378
BS02 HEM A E56 I79 H86 R90 I230 G233 G234 T237 T238 V280 R285 A335 F336 G337 F338 H341 C343 G345 A349 E51 I74 H81 R85 I225 G228 G229 T232 T233 V275 R280 A330 F331 G332 F333 H336 C338 G340 A344
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0008395 steroid hydroxylase activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0036199 cholest-4-en-3-one 26-monooxygenase activity
GO:0046872 metal ion binding
Biological Process
GO:0006707 cholesterol catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7smz, PDBe:7smz, PDBj:7smz
PDBsum7smz
PubMed35881654
UniProtB2HI07

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