Structure of PDB 7sl5 Chain A

Receptor sequence

>7sl5A (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]

VQLVQSGGGVVQPGESLRLSCSGSGFTFNNYIMHWVRQAPGQGLDYVSGI
GSDGRNTNYGDSVKGRFTISRDNSKDTLYLQMTSLRAEDTAFYYCVKGLD
VLRFLDLSTPSGERLDAFDIWGQGTMVTVSSASTKGPSVFPLAPSSSGGT
AALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVP
SSSLGTQTYICNVNHKPSNTKVDKRVEP

3D structure

PDB

7sl5 ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.

Chain

Resolution

2.5 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	N31 G52 S53 D54 R56 N57 T58 D101 V102 L103	N30 G51 S52 D53 R55 N56 T57 D100 V101 L102

External links

PDB	RCSB:7sl5, PDBe:7sl5, PDBj:7sl5
PDBsum	7sl5
PubMed	35857703

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