Structure of PDB 7skq Chain A

Receptor sequence
>7skqA (length=313) Species: 347537 (Bat SARS CoV Rf1/2004) [Search protein sequence]
VKTIKVFTTVDNTNLHTQLVDMSMTYGQHFGPTYLDGADVTKVKPHVNHE
GKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGL
TSIKWADNNCYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALI
LAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNLVCKHCGQKTTTLMG
VEAVMYMGTLSYDELKAGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEY
KLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT
DVFYKETSYTTTI
3D structure
PDB7skq Exploring Noncovalent Protease Inhibitors for the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses.
ChainA
Resolution3.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C190 C193 C225 C227 C188 C191 C223 C225
BS02 ZN A H90 D109 H88 D107
BS03 TTT A P249 Y265 Y269 Q270 P247 Y263 Y267 Q268
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:7skq, PDBe:7skq, PDBj:7skq
PDBsum7skq
PubMed35199517
UniProtQ0QDZ2

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