Structure of PDB 7sh4 Chain A

Receptor sequence
>7sh4A (length=272) Species: 9606 (Homo sapiens) [Search protein sequence]
SFHVIWIASFYNHSWKQNLVSGWLSDLQTHTWDSNSSTIVFLWPWSRGNF
SNEEWKELETLFRIRTIRSFEGIRRYAHELQFEYPFEIQVTGGCELHGSF
LQLAYQGSDFVSFQNNSWLPYPVAGNMAKHFCKVLNQNQHENDITHNLLS
DTCPRFILGLLDAGKAHLQRQVKPEAWLSHGPSPGPGHLQLVCHVSGFYP
KPVWVMWMRGEQEQQGTQRGDILPSADGTWYLRATLEVAAGEAADLSCRV
KHSSLEGQDIVLYWEGSLVPRG
3D structure
PDB7sh4 Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MW9 A W14 A16 N26 V28 S29 T39 W63 R73 T74 R76 S77 F78 G80 I81 I96 L116 L148 C166 F169 W6 A8 N18 V20 S21 T31 W55 R65 T66 R68 S69 F70 G72 I73 I88 L103 L135 C153 F156
External links
PDB RCSB:7sh4, PDBe:7sh4, PDBj:7sh4
PDBsum7sh4
PubMed36550321
UniProtP06126|CD1A_HUMAN T-cell surface glycoprotein CD1a (Gene Name=CD1A)

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